Pyrrolidine, 2-(trifluoromethyl)-
2-(Trifluoromethyl)pyrrolidine
CAS: 119618-29-0;109074-67-1
Molecular Formula: C5H8F3N
Pyrrolidine, 2-(trifluoromethyl)- - Names and Identifiers
| Name | 2-(Trifluoromethyl)pyrrolidine |
| Synonyms | 2-(TRIFLUOROMETHYL)PYRROLIDINE 2-(Trifluoromethyl)pyrrolidine DL-2-Trifluoromethylpyrrolidine 2-(Trifluoromethyl)-pyrrolidine DL-2-TRIFLUOROMETHYLPYRROLIDINE Pyrrolidine, 2-(trifluoromethyl)- (2R)-2-(trifluoromethyl)pyrrolidine 2(R)-2-(Trifluoromethyl)pyrrolidine 1-Aza-2-(trifluoromethyl)cyclopentane (R)-(-)-2-(Trifluoromethyl)PYRROLIDINE (R)-1-cyclopentyl-2,2,2-trifluoroethanamine 1,1'-(1,1,1,3,3,3-hexafluoropropane-2,2-diyl)bis(4-methylbenzene) |
| CAS | 119618-29-0 109074-67-1 |
| InChI | InChI=1/C5H8F3N/c6-5(7,8)4-2-1-3-9-4/h4,9H,1-3H2/t4-/m1/s1 |
Pyrrolidine, 2-(trifluoromethyl)- - Physico-chemical Properties
| Molecular Formula | C5H8F3N |
| Molar Mass | 139.12 |
| Density | 1.210g/mLat 25°C |
| Melting Point | 29-33 |
| Boling Point | 104-106°C |
| Flash Point | 78°F |
| Vapor Presure | 60.3mmHg at 25°C |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.379 |
| MDL | MFCD02663405 |
Pyrrolidine, 2-(trifluoromethyl)- - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms R11 - Highly Flammable |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S16 - Keep away from sources of ignition. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Note | Flammable/Harmful |
| Hazard Class | 4.1 |
| Packing Group | III |
Pyrrolidine, 2-(trifluoromethyl)- - Introduction
2-(Trifluoromethyl) pyrrolidine is an organic compound with the chemical formula C5HF3N. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-(Trifluoromethyl) pyrrolidine is a colorless to pale yellow liquid.
-melting point: about -87 ℃
-Boiling point: about 36-38 ℃
-Density: about 1.47g/cm³
-relative molecular mass: 129.06g/mol
-Solubility: 2-(Trifluoromethyl) pyrrolidine is soluble in common organic solvents such as ethanol, acetone and dimethyl sulfoxide.
Use:
-As a solvent: 2-(Trifluoromethyl) pyrrolidine is a commonly used organic solvent that can be used to dissolve and dilute some chemicals.
-Reagent in chemical reactions: The compound can be used as a reagent for some organic synthesis reactions, such as alkylation reactions, electrophilic substitution and fluorination reactions.
Preparation Method:
2-(trifluoromethyl) pyrrolidine has many preparation methods. The following is one of the commonly used methods:
-Reaction of pyrrolidine with trifluoromethyl thiourea under basic conditions to produce 2-(trifluoromethyl) pyrrolidine.
Safety Information:
Due to the high safety of 2-(trifluoromethyl) pyrrolidine, there is no report that it causes obvious harm to human health or the environment. However, as an organic solvent, it still has some general hazards of common organic solvents, such as skin irritation and eye irritation. When using this compound, appropriate laboratory safety measures should be taken, including the use of gloves, safety glasses and ventilation facilities. After contact with skin or eyes, rinse with water immediately and seek medical attention in severe cases. When using or handling the compound, care should be taken to avoid inhalation of its vapors or contact with its liquids. Storage should be sealed and stored in a cool, dry place, away from fire and oxidant.
Nature:
-Appearance: 2-(Trifluoromethyl) pyrrolidine is a colorless to pale yellow liquid.
-melting point: about -87 ℃
-Boiling point: about 36-38 ℃
-Density: about 1.47g/cm³
-relative molecular mass: 129.06g/mol
-Solubility: 2-(Trifluoromethyl) pyrrolidine is soluble in common organic solvents such as ethanol, acetone and dimethyl sulfoxide.
Use:
-As a solvent: 2-(Trifluoromethyl) pyrrolidine is a commonly used organic solvent that can be used to dissolve and dilute some chemicals.
-Reagent in chemical reactions: The compound can be used as a reagent for some organic synthesis reactions, such as alkylation reactions, electrophilic substitution and fluorination reactions.
Preparation Method:
2-(trifluoromethyl) pyrrolidine has many preparation methods. The following is one of the commonly used methods:
-Reaction of pyrrolidine with trifluoromethyl thiourea under basic conditions to produce 2-(trifluoromethyl) pyrrolidine.
Safety Information:
Due to the high safety of 2-(trifluoromethyl) pyrrolidine, there is no report that it causes obvious harm to human health or the environment. However, as an organic solvent, it still has some general hazards of common organic solvents, such as skin irritation and eye irritation. When using this compound, appropriate laboratory safety measures should be taken, including the use of gloves, safety glasses and ventilation facilities. After contact with skin or eyes, rinse with water immediately and seek medical attention in severe cases. When using or handling the compound, care should be taken to avoid inhalation of its vapors or contact with its liquids. Storage should be sealed and stored in a cool, dry place, away from fire and oxidant.
Last Update：2024-04-10 22:29:15
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Multiple Specifications
Product Name: (+/-)-2-(Trifluoromethyl)Pyrrolidine Visit Supplier Webpage Request for quotationCAS: 109074-67-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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